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sparsentan will reduce the extent or result of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Watch. Sparsentan (a CYP2C19 inducer) decreases publicity of CYP2C19 substrates and cuts down efficacy related to these substrates.Too much sleepiness is The shortcoming to remain awake in the course of cases when wake-fulness and al